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Table 3 Summary of characteristics of approved RSV vaccines for older adults

From: Prevention of respiratory syncytial virus disease across the lifespan in Italy

 

RSVPreF [17]

RSVPreF3 [20]

mRNA-1345 [21]

Technology

Protein

Protein

mRNA

Targeted antigen

Prefusion F protein from RSV subgroups A + B (bivalent)

Prefusion F protein from RSV subgroup A

Prefusion F protein from RSV subgroup A

Adjuvated

No

Yes

No

Content

60 µg + 60 µg prefusion F protein

120 µg prefusion F protein

50 µg mRNA for prefusion F protein

Number of doses

Single

Single

Single