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Table 1 Demographic data, clinical pathological and behavior aspects and specific interventions during hospitalizationaccordingto the NITR success and failure

From: Oxygenation indices and early prediction of outcome in hypoxemic patients with COVID-19 pneumonia requiring noninvasive respiratory support in pulmonary intermediate care unit

Parameters

All patients

Patients Group

Logistic regression model adjusted for age

Multivariate analysis

NIRT success

NIRT failure

p

OR

p

95% CI

OR

p

95% CI

General

 Age (years) (mean±SD)

69,2±14,5

65,7±13,9

80,7±9,5

<0,0001

-

-

-

1,07

0,004

1,02-1,11

 Male

227 (61,7%)

171 (75,3%)

56 (24,7%)

0,455

1,74

0,049

1,00-3,04

2,73

0,005

 1,35-5,53

 DNI (do not intubate order)

 71 (19,3%)

10 (14,1%)

61 (85,9%)

<0,0001

31

<0,0001

 14,34-66,96

   

 Time in NIRT (h)

9,9±7,6

9,5±6,6

11,1±10,3

0,10

1

0,738

0,97-1,04

   

Clinical pathological and behaviour aspects

 Charlson index >3

177 (48,1%)

102 (57,6%)

75 (42,4%)

<0,0001

2,82

0,025

1,14-6,95

1,84

 0,261

 0,64-5,33

 Neurological comorbidities

62 (16,8%)

33 (53,2%)

29 (46,8%)

<0,0001

2,08

0,028

1,08-3,98

1,26

0,576

0,57-2,78

 Psychiatric comorbidities

70 (19,0%)

58 (82,7%)

12 (17,1%)

0,171

0,67

0,284

0,32-1,40

   

 Delirium

27 (7,3%)

14 (51,9%)

13 (48,1%)

0,002

2,17

0,085

 0,90-5,25

   

 Agitation/confusion

140 (38,0%)

73 (52,1%)

 67 (47,9%)

<0,0001

5,51

<0,0001

2,96-10,25

2,42

0,021

1,14-5,14

 Diabetes

77 (20,9%)

64 (83,1%)

13 (16,9%)

0,13

0,6

0,166

 0,29-1,24

   

 Cardiovascular comorbidities

84 (22,8%)

53 (63,1%)

31 (36,9%)

0,001

1,02

0,957

 0,55-1,88

   

Specific interventions during hospitalization

 No Pronation

102 (27,7%)

55 (53,9%)

47 (46,1%)

<0,0001

2,84

0,001

1,57-5,14

3,65

0,001

1,74-7,62

 Sedation

190 (51,6%)

113 (59,5%)

77 (40,5%)

<0,0001

9,07

<0,0001

4,21-19,58

8,53

<0,0001

3,47-21,00

  1. Logistic regression model performed for NIRT failure: individual parameters with age and model with parameters independently associated with NIRT failure