Table 2 Odds ratios (OR) for clinical outcomes, by phenotype – Mean [95% CI]

Severity

Low

4.4829

4.2870

4.7114

0.3737

0.4051

0.3421

0.1225

0.0974

0.1484

[3.5994, 5.5959]

[3.1414, 5.8774]

[3.4344, 6.4979]

[0.3000, 0.4646]

[0.2975, 0.5498]

[0.2478, 0.4698]

[0.0659, 0.2126]

[0.0340, 0.2280]

[0.0638, 0.3063]

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

Medium

0.8850

0.8386

0.9357

1.4314

1.5583

1.3103

0.3983

0.3128

0.4875

[0.6646, 1.1780]

[0.5553, 1.2624]

[0.6200, 1.4137]

[1.0733, 1.9077]

[1.0347, 2.3500]

[0.8612, 1.9852]

[0.1837, 0.7718]

[0.0812, 0.8652]

[0.1685, 1.1579]

p=0.3983

p=0.4269

p=0.7643

p=0.0119

p=0.0272

p=0.1818

p=0.0031

p=0.0218

p=0.1178

High

0.2220

0.2370

0.2071

2.2210

1.9638

2.5298

8.7970

11.3933

7.0488

[0.1766, 0.2783]

[0.1705, 0.3274]

[0.1491, 0.2858]

[1.7909, 2.7567]

[1.4484, 2.6668]

[1.8535, 3.4607]

[5.5796, 14.3584]

[5.6520, 25.4517]

[3.8353, 13.7154]

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

Mortality

0.0855

0.0806

0.0885

3.1793

2.8226

3.5956

5.3797

6.1221

4.7268

[0.0538, 0.1310]

[0.0384, 0.1538]

[0.0468, 0.1568]

[2.3714, 4.2823]

[1.8511, 4.3479]

[2.3698, 5.5065]

[3.6546, 7.9024]

[3.4975, 10.6876]

[2.7092, 8.1871]

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001

\(p<\)0.001