Skip to main content

Table 2 Factors that correlated with lung mechanic properties per auscultatory session

From: Back to the future: the novel art of digital auscultation applied in a prospective observational study of critically ill Covid-19 patients

Factor

Lung static compliance

Lung resistance

Oxygenation index

Ventilation equilibrium

Standardized coefficients (r)

P (Value)

Standardized coefficients (r)

P (Value)

Standardized coefficients (r)

P (Value)

Standardized coefficients (r)

P (Value)

Daily SOFA score

-0.170

< 0.001

0.370

< 0.001

0.377

< 0.001

-0.060

0.19

CRP (mg/dl)

-0.081

0.13

-0.027

0.73

0.297

< 0.001

-0.050

0.35

PCT (ng/ml)

-0.056

0.27

0.023

0.76

0.101

0.042

0.019

0.71

Day in ICU

0.117

0.011

0.319

< 0.001

-0.023

0.60

0.223

< 0.001

Auscultatory sound: normal (%)

-0.002

0.97

-0.110

0.11

-0.037

0.40

-0.016

0.73

Auscultatory sound: wheezing (%)

-0.074

0.11

0.178

0.009

0.081

0.06

-0.059

0.20

Auscultatory sound: rhonchi (%)

0.137

0.003

-0.083

0.22

-0.111

0.011

0.107

0.020

Auscultatory sound: velcro (%)

0.040

0.39

0.118

0.08

0.080

0.07

-0.019

0.67

Auscultatory sound: crackles (%)

-0.017

0.71

0.017

0.80

0.030

0.49

0.009

0.85

Auscultatory sound: squawks (%)

-0.125

0.006

0.337

< 0.001

0.233

< 0.001

-0.036

0.44

Auscultatory sound: tubular (%)

-0.060

0.19

-0.066

0.34

0.094

0.032

0.019

0.67

Auscultatory sound: diminished (%)

0.054

0.24

-0.198

0.004

-0.211

< 0.001

-0.014

0.76

Auscultatory sound: absence (%)

0.108

0.018

-0.198

0.003

-0.143

0.001

-0.014

0.76

minimum crackle entropy

-0.034

0.47

0.079

0.25

0.018

0.68

0.073

0.11

minimum crackle harmonic ratio

-0.072

0.12

0.164

0.016

0.092

0.036

0.006

0.89

minimum spectral entropy

0.000

0.99

0.065

0.35

0.074

0.09

0.016

0.73

minimum spectral brightness 800 ratio

0.034

0.46

-0.274

< 0.001

-0.104

0.017

0.043

0.35

median crackle duration (s)

0.065

0.16

0.061

0.37

0.026

0.56

0.124

0.007

median crackle zero-crossing rate

-0.018

0.70

-0.103

0.13

-0.049

0.27

-0.036

0.44

median crackle entropy

-0.107

0.021

0.055

0.42

0.079

0.07

-0.008

0.86

median crackle harmonic ratio

0.009

0.85

0.047

0.50

-0.016

0.72

-0.020

0.66

median squawk zero-crossing rate

-0.026

0.57

-0.019

0.78

-0.027

0.55

-0.017

0.71

median spectral entropy

-0.078

0.09

0.119

0.08

0.100

0.023

0.017

0.71

median spectral irregularity

0.200

< 0.001

-0.238

< 0.001

-0.222

< 0.001

0.126

0.006

maximum crackle centroid (Hz)

0.095

0.039

-0.161

0.018

-0.201

< 0.001

0.012

0.79

maximum crackle harmonic ratio

0.166

< 0.001

-0.067

0.33

-0.169

< 0.001

0.015

0.75

mean crackle frequency range (Hz)

-0.019

0.68

-0.171

0.012

-0.062

0.16

-0.046

0.32

mean crackle entropy

-0.092

0.046

0.018

0.80

0.057

0.19

0.038

0.41

mean crackle harmonic ratio

0.046

0.31

0.035

0.61

-0.054

0.22

-0.004

0.92

standard deviation spectral entropy

-0.053

0.25

-0.019

0.78

-0.020

0.65

-0.004

0.93

  1. CI = confidence intervals, SOFA: sequential organ failure assessment, CRP = c reactive protein, PCT = procalcitonin, ICU = intensive care unit. Bold numbers indicate statistically significant correlations