Invasive pulmonary aspergillosis among patients with severe community-acquired pneumonia and influenza in ICUs: a retrospective cohort study

Table 3 Multivariate logistic regression of the risk factors for invasive pulmonary aspergillosis in patients with severe non-influenza CAP or severe influenza

Factors	Risk for invasive pulmonary aspergillosis
Factors	OR	95% CI	P value
All patients
Influenza vs. non-influenza CAP	0.568	0.243–1.326	0.191
COPD	2.993	1.232–7.276	0.016^*
ICS 28 days before ICU	3.782	1.009–14.177	0.048^*
Severe CAP patients
COPD	1.764	0.580–5.364	0.317
ICS 28 days before ICU	4.333	1.010–18.585	0.048^*
Severe influenza pneumonitis patients
COPD	11.294	1.883–67.733	0.008^*
ICS 28 days before ICU	2.883	0.094–88.435	0.544

OR Odds ratio, 95% CI 95% confidence interval, CAP community acquired pneumonia, COPD chronic obstructive pulmonary disease, ICS inhaled corticosteroid
^* P < 0.05

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