Fig. 4
Histomorphometric measurements of inflammatory granulomas areas of lung tissues of Wistar rats. Measures (μm2) of parenchymal lesions surfaces of inflamed lungs of male (A) and female (B) Wistar rats showing the significant difference between each dose (1.5 × 105, 1.5 × 106, 1.5 × 107 or 1.5 × 10.8 CFU/mL) on days 0, 5, 10 and 15 PI. All results were mean ± SD of six animals per group. Histomorphometric measurements were analysed using Dunnett’s post-test (*: p < 0.05; **: p < 0.01; ***: p < 0.001); Days post-inoculation 5, 10 and 15 vs Day 0