Fig. 1
From: Acute organ injury and long-term sequelae of severe pneumococcal infections

Consequences of pneumococcal disease during acute infection occur system-wide. Acute pneumococcal pneumonia and invasive disease can be life-threatening. It can also result in organ damage that results in debilitating long-term sequelae. These sequelae, in turn, contribute to loss of physiological resilience and early mortality