Fig. 1

Distribution of the patients in the cohorts CAP1 and CAP2 in general and considering the approaches analyzing both cohorts, unmatched and matched. The unmatched patients, both from CAP1 and CAP2 cohorts, were excluded because they had no pair with comparable age, sex and PSI score. The number of patients excluded from the case-control analysis were 162 from the CAP1 and 46 from the CAP2 cohorts